DeepLIIF is a virtual multiplex immunofluorescence (mpIF) restaining technique for immunohistochemistry (IHC) images. Given an IHC image input (brightfield Hematoxylin + DAB protein), DeepLIIF infers high-quality mpIF DAPI (nuclear), mpIF LAP2Beta (nuclear envelope), mpIF protein marker, and semantic segmentation (blue/red cell segmentation masks for IHC scoring). DeepLIIF also generates high-quality mpIF modalities out-of-the-box for H&E images as well.
PLEASE READ THIS DOCUMENT CAREFULLY BEFORE YOU ACCESS OR USE DEEPLIIF. BY ACCESSING ANY PORTION OF DEEPLIIF, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH BELOW. IF YOU DO NOT WISH TO BE BOUND BY THESE TERMS AND CONDITIONS, PLEASE DO NOT ACCESS DEEPLIIF.
DeepLIIF is developed and maintained by Memorial Sloan Kettering Cancer Center (“MSK,” “we”, or “us”) to provide an experimental artificial intelligence driven tool to translate IHC images to more informative mpIF representations, auto-segment relevant cells, and quantify protein expression for more accurate and reproducible IHC quantification. MSK may, from time to time, update the software and other content on https://deepliif.org/ (“Content”). MSK makes no warranties or representations, and hereby disclaims any warranties, express or implied, with respect to any of the Content, including as to the present accuracy, completeness, timeliness, adequacy, or usefulness of any of the Content. By using this website, you agree that MSK will not be liable for any losses or damages arising from your use of or reliance on the Content, or other websites or information to which this website may be linked.
By providing images to be analyzed using DeepLIIF (Submitted Images), you authorize MSK to copy, modify, display, distribute, perform, use, publish, and otherwise exploit the Submitted Images for any and all purposes, all without compensation to you, for as long as we decide (collectively, the "Use Rights"). In addition, you authorize us to grant any third party some or all of the Use Rights. By way of example, and not limitation, the Use Rights include the right for us to publish Submitted Images in whole or in part, and whether cropped, adopted, altered, or otherwise manipulated, for as long as we choose. By providing Submitted Images, you represent and warrant that (i) you own all rights in and to the Submitted Images (including any related copyrights or other intellectual property rights) or have sufficient authority and right to provide the content and to grant the Use Rights; (ii) your submission of the images and grant to us of Use Rights do not violate or conflict with the rights of other persons, or breach your obligations to other persons; and (iii) the Submitted Images do not include or contain any personally identifiable information (PII) or protected health information (PHI).
DO NOT submit personally identifiable information (PII) or protected health information (PHI) in connection with any Submitted Images or otherwise.
Without limiting the generality of the foregoing, you may not use any part of the DeepLIIF, the underlying Content or the output for any other purpose, including:
use or incorporation into a commercial product or towards the performance of a commercial service;
research use in a commercial setting;
use for patient care or the provision of medical services; or
generation of reports in a medical, laboratory, hospital or other patient care setting.
You may not copy, transfer, reproduce, modify or create derivative works of DeepLIIF or the underlying Content for any commercial purpose without the express permission of MSK.
The image output of DeepLIIF and the underlying Content is not a substitute for professional medical help, judgment or advice. Use of DeepLIIF does not create a physician-patient relationship or in any way make a person a patient of MSK. A physician or other qualified health provider should always be consulted for any health problem or medical condition.
Neither these Terms or Use nor the availability of DeepLIIF should be understood to create an obligation or expectation that MSK will continue to make DeepLIIF available. MSK may discontinue or restrict the availability of DeepLIIF at any time. MSK may also modify these Terms or Use at any time.
MSK respects the intellectual property rights of others, just as it expects others to respect its intellectual property. If you believe that any content (including Submitted Images and Content) on the website or other activity taking place on the website constitutes infringement of a work protected by copyright, please notify us at:
Your notice must comply with the Digital Millennium Copyright Act (17 U.S.C. §512) (the "DMCA"). Upon receipt of a compliant notice, we will respond and proceed in accordance with the DMCA.
For inquiries about the Content, please contact us.